BDBM50428033 CHEMBL2325505

SMILES COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(cc3s2)C(F)(F)F)nc2CCSc2c1=O

InChI Key InChIKey=IWRAAGLSFNDBOE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428033   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
The University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428033(CHEMBL2325505)
Affinity DataEC50:  30nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed