BDBM50428029 CHEMBL1257063

SMILES COc1ccc(cc1)-n1nc(C(=O)NCC(=O)Nc2nc3ccc(OC)cc3s2)c2ccccc2c1=O

InChI Key InChIKey=WLWIHRXVYJONEJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428029   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Human)
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50428029(CHEMBL1257063)
Affinity DataIC50: 60nMAssay Description:Inhibition of porcupine activity (unknown origin) expressed in human HT1080 cells assessed as suppression of Wnt3A-mediated super top flash activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
The University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428029(CHEMBL1257063)
Affinity DataEC50:  60nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed