BDBM50427868 CHEMBL2326366

SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccc(OCCF)cc1

InChI Key InChIKey=UIVFNXLDHQCJRY-UHFFFAOYSA-N

Data  7 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50427868   

Target72 kDa type IV collagenase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataKd:  15nMAssay Description:Binding affinity to MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlbumin(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataKd:  1.40E+5nMAssay Description:Binding affinity to human serum albumin by 19F NMR titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 22nMAssay Description:Inhibition of MMP-13 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 44nMAssay Description:Inhibition of MMP-12 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 107nMAssay Description:Inhibition of MMP-9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of MMP-3 (unknown origin) using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys-(Dnp)-NH2 as substrate after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 16nMAssay Description:Inhibition of MMP-2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50427868(CHEMBL2326366)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of MMP-1 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed