BDBM50427840 CHEMBL2326074

SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCC#Cc1ccc(cc1)-c1ccno1)Cc1cc(O)ccc31

InChI Key InChIKey=BTKBDYIATAATDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50427840   

TargetSteroid hormone receptor ERR1(Human)
University of Kansas Medical Center

Curated by ChEMBL
LigandPNGBDBM50427840(CHEMBL2326074)
Affinity DataIC50: 482nMAssay Description:Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
University of Kansas Medical Center

Curated by ChEMBL
LigandPNGBDBM50427840(CHEMBL2326074)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at ERalpha receptor in human MCF7 cells assessed as inhibition of cell growth after 6 days by crystal violet staining methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetIsoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10)(Human)
University of Kansas Medical Center

Curated by ChEMBL
LigandPNGBDBM50427840(CHEMBL2326074)
Affinity DataIC50: 331nMAssay Description:Displacement of [3H]E2 from human recombinant ERbeta receptor after overnight incubation by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed