BDBM50427772 CHEMBL2325183

SMILES c1ccc(cc1)C(=O)CNC(=O)Nc2ccc3c(c2)snn3

InChI Key InChIKey=PKHSKYFMULMNOC-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427772   

TargetProtein arginine N-methyltransferase 3 [N508S](Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50427772(CHEMBL2325183)
Affinity DataIC50: 480nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SUV39H2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50427772(CHEMBL2325183)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of SUV39H2 (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50427772(CHEMBL2325183)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GLP (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-aden...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50427772(CHEMBL2325183)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of G9a (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-aden...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed