BDBM50427584 CHEMBL2322918

SMILES Nc1nc(Cc2ccccc2)nc2cn(nc12)-c1ccccc1

InChI Key InChIKey=MLXRXENPLDYOCG-UHFFFAOYSA-N

Data  8 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50427584   

TargetAdenosine receptor A2b(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP level by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP production by scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cell membranes assessed as inhibition of NECA-stimulated cAMP level preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataIC50: 420nMAssay Description:Inhibition of human A2B adenosine receptor transfected in CHO cells assessed as inhibition of NECA-induced cyclic AMP production after 10 mins by com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]ZM241385 at human A2A receptor expressed in CHO cell membrane after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]ZM241385 from human A2A adenosine receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]DPCPX at human A1 receptor expressed in CHO cell membrane after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cell membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50427584(CHEMBL2322918)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]DPCPX from human A1 adenosine receptor expressed in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed