BDBM50427282 CHEMBL2325418

SMILES Cc1ccc(cc1C)C(CCC(N)C(O)=O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=RXRRTVLGWNBXDX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50427282   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50427282(CHEMBL2325418)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERG channel expressed in CHO cells by Ionworks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50427282(CHEMBL2325418)
Affinity DataKi:  9.90nMAssay Description:Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50427282(CHEMBL2325418)
Affinity DataKi:  12nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed