BDBM50427055 CHEMBL2322536

SMILES C[C@@H](C(=O)NCc1ccc(CN)cc1)c1ccc(c(F)c1)-c1ccccc1

InChI Key InChIKey=FHYZRKQSKXWLMZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427055   

TargetBeta-secretase 1(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50: 8.57E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50: 7.71E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50427055(CHEMBL2322536)
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed