BDBM50427045 CHEMBL2322830

SMILES O=C(Cc1ccc(cc1)-c1ccccc1)NCc1ccc(CN2Cc3ccccc3C2)cc1

InChI Key InChIKey=YXDJXWNOSXNEIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427045   

TargetBeta-secretase 1(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50427045(CHEMBL2322830)
Affinity DataIC50: 6.33E+4nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50427045(CHEMBL2322830)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed