BDBM50426993 CHEMBL2326539

SMILES CC(C)[C@H](NC(=O)c1cccc(O)c1C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O

InChI Key InChIKey=YHIZZZRSMFJLII-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50426993   

TargetProteasome subunit beta type-5(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426993(CHEMBL2326539)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426993(CHEMBL2326539)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of trypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426993(CHEMBL2326539)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of caspase-like activity of proteasome in human NCI-H929 cells at 200 uM after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426993(CHEMBL2326539)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426993(CHEMBL2326539)
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426993(CHEMBL2326539)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of caspase-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed