BDBM50426888 CHEMBL2323694

SMILES CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(CCCC(=O)NC(C)(C)C(=O)N2CCNCC2)cc1

InChI Key InChIKey=XLGGPHXVLBTVEQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426888   

TargetSodium/glucose cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426888(CHEMBL2323694)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426888(CHEMBL2323694)
Affinity DataIC50: 104nMAssay Description:Inhibition of rat SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426888(CHEMBL2323694)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426888(CHEMBL2323694)
Affinity DataIC50: 50nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed