BDBM50426575 CHEMBL2324347
SMILES CC(C)NCCN(C(C)C)S(=O)(=O)c1ccc(Cl)cc1Cl
InChI Key InChIKey=IHYZMEAZAIFMTN-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50426575
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of TRPV4 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced intracellular calcium after 10 mins in pres...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced intracellular calcium after 10 mins in presen...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Mouse)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at mouse TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced intracellular calcium after 10 mins in pres...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at TRPV4 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human TRPV4More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Mouse)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at mouse TRPV4More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at rat TRPV4More data for this Ligand-Target Pair