BDBM50426561 CHEMBL2323965

SMILES Cc1cnc(C)c2nc(nn12)-c1ccn2cc(nc2c1)-c1ccccc1

InChI Key InChIKey=IQYYYEWMSRLEIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426561   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50426561(CHEMBL2323965)
Affinity DataIC50: 0.100nMpH: 7.4Assay Description:The PDE10 inhibition assay in 384-well plates was conducted to identify substances for the inhibition of cyclic nucleotide hydrolysis by the PDE10 en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
Go to US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50426561(CHEMBL2323965)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE10A (unknown origin) by LE-PDE10A inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50426561(CHEMBL2323965)
Affinity DataIC50: 37nMAssay Description:Inhibition of PDE10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed