BDBM50426531 CHEMBL2323935
SMILES CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C#N
InChI Key InChIKey=VQMVPKAEWRRWNJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50426531
TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at rat TRPV4More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in BacMam virus infected HEK MSRII cells assessed as inhibition of GSK1016790A-induced calci...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human TRPV4More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at TRPV4 (unknown origin)More data for this Ligand-Target Pair