BDBM50426443 CHEMBL2322374::US20250017938, Compound 001-31

SMILES Cc1ccc(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2cc(ncc2[nH]1)N1CCCC1

InChI Key InChIKey=HWQONTIWVVHWEW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426443   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM50426443(CHEMBL2322374 | US20250017938, Compound 001-31)
Affinity DataIC50: 60nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetFatty acid synthase(Rat)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426443(CHEMBL2322374 | US20250017938, Compound 001-31)
Affinity DataIC50: 635nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM50426443(CHEMBL2322374 | US20250017938, Compound 001-31)
Affinity DataIC50: 60nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM50426443(CHEMBL2322374 | US20250017938, Compound 001-31)
Affinity DataIC50: 60nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent