BDBM50426341 CHEMBL2321944

SMILES N[C@H]1Cc2cc(Oc3ccccc3)ccc2N(O)C1=O

InChI Key InChIKey=COBQSWIQOSRUIK-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426341   

TargetKynurenine--oxoglutarate transaminase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKynurenine--oxoglutarate transaminase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataIC50: 23nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50426341(CHEMBL2321944)
Affinity DataKi:  7.10nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed