BDBM50425707 CHEMBL2315920::US9062048, 107

SMILES FC(F)(F)c1ccc2ncnc(NCC(=O)NC3CN(C3)[C@H]3CC[C@H](CC3)c3ccccc3)c2c1

InChI Key InChIKey=LRKGQBKBMALHOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425707   

TargetC-C chemokine receptor-like 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50425707(CHEMBL2315920 | US9062048, 107)
Affinity DataIC50: 15nMAssay Description:Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va., USA). The THP-1 cells were grown in RPMI-16...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425707(CHEMBL2315920 | US9062048, 107)
Affinity DataIC50: 15nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425707(CHEMBL2315920 | US9062048, 107)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed