BDBM50425694 CHEMBL2315933

SMILES Nc1cccnc1[C@@H]1CC[C@@H](CC1)N1CC(C1)NC(=O)CNc1ncnc2ccc(cc12)C(F)(F)F

InChI Key InChIKey=GEASWLLRXOGPGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425694   

TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425694(CHEMBL2315933)
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425694(CHEMBL2315933)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed