BDBM50425152 CHEMBL2313562

SMILES C(N1CCCCC1)c1cc2ccc(Oc3nc4ncccc4s3)cc2o1

InChI Key InChIKey=SHQARKWHJUQQBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425152   

TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425152(CHEMBL2313562)
Affinity DataIC50: 140nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425152(CHEMBL2313562)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed