BDBM50425150 CHEMBL2313564

SMILES C(N1CCOCC1)c1coc2cc(Oc3nc4ccccc4s3)ccc12

InChI Key InChIKey=NHQCIXXCPKITFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425150   

TargetLeukotriene A-4 hydrolase(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425150(CHEMBL2313564)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of LTA4H in CD1 mouse whole blood assessed as decrease in calcium ionophore-stimulated LTB4 production incubated for 15 mins prior to calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425150(CHEMBL2313564)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed