BDBM50425122 CHEMBL2313235

SMILES Cc1nc2ccc(CNCc3ccccc3)cc2n2c(nnc12)-c1ccccc1Cl

InChI Key InChIKey=LSOKSPALIMSVDM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425122   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425122(CHEMBL2313235)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425122(CHEMBL2313235)Copy SMILESCopy InChI

Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL