BDBM50424996 CHEMBL2312168

SMILES Cc1cc(C)cc(c1)C(=O)NOCCCCCC(=O)NO

InChI Key InChIKey=VRYZCEONIWEUAV-UHFFFAOYSA-N

Data  4 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50424996   

TargetHistone deacetylase 11(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 852nMAssay Description:Inhibition of human HDAC11 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 320nMAssay Description:Inhibition of human HDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 56nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC4 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 881nMAssay Description:Inhibition of human HDAC2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 170nMAssay Description:Inhibition of HDAC in human A2780 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 550nMAssay Description:Inhibition of HDAC in human Cal27 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(Ac)-pNA as substrate preincubated for 20 mins followed by substrate addition and further incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataKi:  80nMAssay Description:Inhibition of recombinant human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataKi:  4.81E+3nMAssay Description:Inhibition of recombinant human HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant human HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed