BDBM50424967 CHEMBL2316148::US9409845, Table 1, Compound 9: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(4-chlorobenzylidene)cyclohexanone

SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccc(Cl)cc3)C2=O)c1

InChI Key InChIKey=YTJPZUZXESULTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424967   

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandPNGBDBM50424967(CHEMBL2316148 | US9409845, Table 1, Compound 9: (2...)
Affinity DataIC50: 1.53E+4nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Pharmaxyn Laboratories

US Patent
LigandPNGBDBM50424967(CHEMBL2316148 | US9409845, Table 1, Compound 9: (2...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed