BDBM50424747 CHEMBL2314175::US10093640, Example 3::US10844032, Example 3

SMILES OC(=O)c1sc2cccc(Cl)c2c1CCCOc1cccc2ccccc12

InChI Key InChIKey=JJQKEUXKXRKWFY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424747   

LigandPNGBDBM50424747(CHEMBL2314175 | US10093640, Example 3 | US10844032...)
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
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LigandPNGBDBM50424747(CHEMBL2314175 | US10093640, Example 3 | US10844032...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50424747(CHEMBL2314175 | US10093640, Example 3 | US10844032...)
Affinity DataKi:  5.50E+3nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent