BDBM50424735 CHEMBL2314193

SMILES Cc1cc(OCCCc2c([nH]c3ccccc23)C(O)=O)cc(C)c1Cl

InChI Key InChIKey=FQKXEZIKGBCCDX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424735   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424735(CHEMBL2314193)
Affinity DataKi:  300nMAssay Description:Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424735(CHEMBL2314193)
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of FITC-AHx-GQVGRQLAIIGDDINR-NH2 from Bcl2 (unknown origin) after 1 hr by fluorescence polarization anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424735(CHEMBL2314193)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of FITC-AHx-GQVGRQLAIIGDDINR-NH2 from Bcl-xL (unknown origin) after 1 hr by fluorescence polarization anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed