BDBM50424473 CHEMBL2316385

SMILES CS(=O)Cc1ccc(C(=O)Nc2nccnc2C(=O)NCC2CCC2)c2ccccc12

InChI Key InChIKey=RSYSXDBUOKOFIE-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50424473   

TargetCannabinoid receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor expressed in Sf9 cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293S cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293S cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in Escherichia coli cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in Escherichia coli cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293S cell membranes after 1 hr by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50424473(CHEMBL2316385)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293S cell membranes after 1 hr by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed