BDBM50424430 CHEMBL2316061

SMILES [NH3+]CCc1c[nH]c2ccc(OCCOc3ccc(Oc4ccccc4[N+]([O-])=O)cc3)cc12

InChI Key InChIKey=RSBLTCHMMIJLMZ-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424430   

TargetLeukotriene A-4 hydrolase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50424430(CHEMBL2316061)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50424430(CHEMBL2316061)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50424430(CHEMBL2316061)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed