BDBM50424429 CHEMBL2316062

SMILES COC(=O)NCCc1c[nH]c2ccc(OCc3ccc(cc3)-c3ccccc3)cc12

InChI Key InChIKey=ZJFBXAWZKFFGEY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424429   

TargetLeukotriene A-4 hydrolase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50424429(CHEMBL2316062)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human LTA4H epoxide hydrolase activity using LTA4 as substrate incubated for 15 mins prior to substrate addition measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50424429(CHEMBL2316062)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human LTA4H aminopeptidase activity using Ala-p-nitroanilide as substrate incubated for 2 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50424429(CHEMBL2316062)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human nonpancreatic secretory phospholipase A2 using 1,2-dimyristoyl-sn-glycero-3-phosphocholine as substrate after 10 mins by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed