BDBM50424343 CHEMBL2314778

SMILES OCC(NCc1ccccc1)c1ccc2c(NC(=O)[C@@H](N=C2c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=GKOVDJKWFAKAGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424343   

TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424343(CHEMBL2314778)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424343(CHEMBL2314778)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed