BDBM50424289 CHEMBL2314442

SMILES CC[C@H](CO)Nc1cncc(Nc2nc3cncnc3n2C(C)C)n1

InChI Key InChIKey=VGAXWFQZQONAPZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424289   

TargetCyclin-dependent kinase 5 activator 1(Human)
University of Paris

Curated by ChEMBL

LigandBDBM50424289(CHEMBL2314442)Copy SMILESCopy InChI

Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Paris

Curated by ChEMBL

LigandBDBM50424289(CHEMBL2314442)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant GST-fused human DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL