BDBM50424271 CHEMBL2314472

SMILES CC[C@@H](CO)Nc1nc(Nc2cccnc2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=VMSMVRDDPGJMQF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424271   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Paris

Curated by ChEMBL

LigandBDBM50424271(CHEMBL2314472)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant GST-fused human DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetCyclin-dependent kinase 5 activator 1(Human)
University of Paris

Curated by ChEMBL

LigandBDBM50424271(CHEMBL2314472)Copy SMILESCopy InChI

Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL