BDBM50424268 CHEMBL2314468

SMILES CC(C)n1c(nc2c(Nc3cccnc3)ncnc12)C(CO)CO

InChI Key InChIKey=MKLNVNFIBKVSOF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424268   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Paris

Curated by ChEMBL

LigandBDBM50424268(CHEMBL2314468)Copy SMILESCopy InChI

Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant GST-fused human DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetCyclin-dependent kinase 5 activator 1(Human)
University of Paris

Curated by ChEMBL

LigandBDBM50424268(CHEMBL2314468)Copy SMILESCopy InChI

Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL