BDBM50424223 CHEMBL2313853

SMILES Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3Cl)c12)C(=O)c1cccc(Cl)c1

InChI Key InChIKey=BXLXOBIMRFZEAE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50424223   

TargetGlycogen synthase kinase-3 beta(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50424223(CHEMBL2313853)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human Nt-GST-tagged GSK-3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50424223(CHEMBL2313853)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nt-GST-tagged GSK-3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Social amoeba)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50424223(CHEMBL2313853)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Dictyostelium discoideum GSK-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPutative glycogen synthase kinase(Leishmania major)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50424223(CHEMBL2313853)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Leishmania major GSK-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase 3(Plasmodium falciparum (isolate 3D7))
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50424223(CHEMBL2313853)
Affinity DataIC50: 480nMAssay Description:Inhibition of Plasmodium falciparum GSK3 measured after 2 hrs by luciferin-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details Article
PubMed
TargetGlycogen synthase kinase 3(Plasmodium falciparum (isolate 3D7))
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50424223(CHEMBL2313853)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant Plasmodium falciparum GSK3 using GS-1 as substrate measured after 30 mins in presence of [gamma 32P-ATP] by SDS-PAGE based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details Article
PubMed