BDBM50423967 CHEMBL2057417

SMILES Cc1nc2sc(C(=O)NCc3ccncc3)c(N)c2c(C)c1Cl

InChI Key InChIKey=XNCQMFVABACABG-UHFFFAOYSA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50423967   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50:  56nMAssay Description:Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat muscarinic M5 receptor assessed as acetylcholine responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic M5 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat muscarinic M3 receptor assessed as acetylcholine responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic M3 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat muscarinic M2 receptor assessed as acetylcholine responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic M2 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat muscarinic M1 receptor assessed as acetylcholine responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic M1 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50423967(CHEMBL2057417)
Affinity DataEC50:  176nMAssay Description:Positive allosteric modulation of rat muscarinic M4 receptor assessed as acetylcholine responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed