BDBM50423673 CHEMBL574663

SMILES CO[C@H]1C[C@@H](CO[C@H]2CC[C@@H](CC2)C(O)=O)N(C1)C(=O)Cc1cc(Cl)c(NC(=O)c2cn(C)c3ccccc23)cc1Cl

InChI Key InChIKey=UPEGZTKVOGNGIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50423673   

TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50423673(CHEMBL574663)
Affinity DataIC50: 5.40nMAssay Description:Displacement of Eu-labeled VCAM-1 from human VLA alpha4 beta1 expressed in CHO-K1 cells after 60 mins by time-resolved fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50423673(CHEMBL574663)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells by fluorimetric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50423673(CHEMBL574663)
Affinity DataIC50: 93nMAssay Description:Inhibition of europium labeled human VCAM1/Fc chimera binding to human VLA-4 alpha-4-beta-1 expressed in Chinese hamster 4B4 cells in presence of 3% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed