BDBM50422757 CHEMBL1969108

SMILES Cc1ccc(cc1)S(=O)(=O)Oc1nc2nc3ccccc3nc2nc1OS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=CPZKCOVBWFYTQJ-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422757   

TargetKelch-like ECH-associated protein 1(Human)
Taizhou University

Curated by ChEMBL
LigandPNGBDBM50422757(CHEMBL1969108)
Affinity DataKd:  114nMAssay Description:Binding affinity to human KEAP1 by SPR direct binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Taizhou University

Curated by ChEMBL
LigandPNGBDBM50422757(CHEMBL1969108)
Affinity DataIC50: 258nMAssay Description:Inhibition of human Keap1-Nrf2 protein-protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50422757(CHEMBL1969108)
Affinity DataKd:  110nMAssay Description:Binding affinity to CM5 chip immobilized GST-tagged mouse KEAP1 Kelch domain (322 to 624 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed