BDBM50421951 CHEMBL1744002

SMILES COc1ccc(CN2CCC3(CCCc4ccccc34)CC2)cc1

InChI Key InChIKey=PUCIJQFBXXTCMC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421951   

TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421951(CHEMBL1744002)
Affinity DataIC50: 1.70nMAssay Description:In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421951(CHEMBL1744002)
Affinity DataIC50: 120nMAssay Description:In vitro for the binding affinity against dopamine receptor D2 by using [3H](-)-sulpiride as radioligand in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50421951(CHEMBL1744002)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50421951(CHEMBL1744002)
Affinity DataKi:  206nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed