BDBM50421849 CHEMBL5283078

SMILES C(CNCc1ccc(CNCCCNC2CCCCC2)cc1)CNC1CCCCC1

InChI Key InChIKey=HAKFGEFAVSVPJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421849   

TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50421849(CHEMBL5283078)
Affinity DataIC50: 20nMAssay Description:Binding affinity to CXCR4 (unknown origin) expressed in CHO cells incubated for 40 mins by competitive binding assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50421849(CHEMBL5283078)
Affinity DataIC50: 119nMAssay Description:Antagonist activity at CXCR4 receptor in SDF-1alpha-stimulated human SUP-T1 cells incubated for 30 mins by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromal cell-derived factor 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50421849(CHEMBL5283078)
Affinity DataIC50: 621nMAssay Description:Inhibition of SDF-1 alpha induced cell migration in human SUP-T1 cells pre-incubated for 30 mins followed by SDF-1 alpha addition measured after 3 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed