BDBM50421841 CHEMBL5270958

SMILES ONC(=O)c1ccc(CN2CC(=O)N[C@@H](Cc3c[nH]c4ccccc34)C2=O)cc1

InChI Key InChIKey=OUWQFNHQQZCXTJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421841   

TargetHistone deacetylase 1(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50421841(CHEMBL5270958)
Affinity DataIC50: 405nMAssay Description:Inhibition of full length C-terminal His/FLAG tagged human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus-infected Sf9 cells using RH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50421841(CHEMBL5270958)
Affinity DataIC50: 6.39E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50421841(CHEMBL5270958)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50421841(CHEMBL5270958)
Affinity DataIC50: 112nMAssay Description:Inhibition of HDAC8 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed