BDBM50421763 CHEMBL2364562

SMILES NC(=O)c1csc(n1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@H](O)[C@@H]1O

InChI Key InChIKey=INQLNSVYIFCUML-UHFFFAOYSA-N

Data  9 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50421763   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataIC50: 90nMAssay Description:The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetAlcohol dehydrogenase E/S chain(Horse)
University of Rochester Medical Center

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKd:  2.70E+4nMAssay Description:Dissociation constant from Alcohol dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  240nMAssay Description:Compound was tested for inhibitory activity against Inosine-5'-monophosphate dehydrogenase, the type of inhibition in not competitiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  430nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Codon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  440nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  470nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  710nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetGlutamate dehydrogenase 1, mitochondrial(Bovine)
University of Rochester Medical Center

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  4.50E+3nMAssay Description:In vitro inhibitory activity against bovine liver glutamate dehydrogenase (GDH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Pig)
University of Rochester Medical Center

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  2.52E+4nMAssay Description:In vitro inhibitory activity against pig heart lactate dehydrogenase (LDH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAlcohol dehydrogenase E/S chain(Horse)
University of Rochester Medical Center

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  2.65E+4nMAssay Description:In vitro inhibitory activity against horse liver Alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Pig)
University of Rochester Medical Center

Curated by ChEMBL
LigandPNGBDBM50421763(CHEMBL2364562)
Affinity DataKi:  3.63E+4nMAssay Description:In vitro inhibitory activity against pig heart cytoplasmic malate dehydrogenase (MDH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed