BDBM50421594 CHEMBL356605

SMILES C(Oc1ccccc1-c1cccnc1)C1=NCCN1

InChI Key InChIKey=VARULOWOKPYQRB-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50421594   

TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421594(CHEMBL356605)
Affinity DataEC50:  2nMAssay Description:Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421594(CHEMBL356605)
Affinity DataEC50:  79nMAssay Description:Activation of recombinant human adrenergic, alpha-1B receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421594(CHEMBL356605)
Affinity DataEC50:  158nMAssay Description:Activation of recombinant human adrenergic, alpha-1D receptor expressed in rat-1 fibroblasts assayed via calcium mobilization through Gq coupled PLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421594(CHEMBL356605)
Affinity DataIC50: 1.29E+3nMAssay Description:Binding affinity of compound towards human Alpha-1B adrenergic receptor expressed in rat fibroblast membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421594(CHEMBL356605)
Affinity DataIC50: 257nMAssay Description:Binding affinity of compound towards human Alpha-1D adrenergic receptor expressed in rat-1 fibroblast membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421594(CHEMBL356605)
Affinity DataIC50: 50nMAssay Description:Binding affinity of compound towards Alpha-1A adrenergic receptor using membranes prepared from Rat-1 fibroblasts expressing human Alpha-1A adrenergi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed