BDBM50421409 CHEMBL318779

SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O

InChI Key InChIKey=RJWLAIMXRBDUMH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50421409   

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50421409(CHEMBL318779)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity was evaluated against recombinant human calpain IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50421409(CHEMBL318779)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of SARS-CoV-2 BetaCoV/Wuhan/WIV04/2019 Main protease expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQ/SGFRKME(Edans) as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50421409(CHEMBL318779)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 6his/TEV-fused GST tagged SARS-CoV-2 MPro (1 to 306 residues) expressed in Escherichia coli RIL cells using 5-FAM-AVLQSGFR-Lys-(Dabcyl)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50421409(CHEMBL318779)
Affinity DataIC50: 970nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50421409(CHEMBL318779)
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed