BDBM50421202 CHEMBL2087291

SMILES OC(=O)Cc1cc(Br)c(N(Cc2ccc(Oc3ccc(Cl)cc3Cl)cc2)Cc2cc(F)cc(F)c2)c(Br)c1

InChI Key InChIKey=JVGQJSSWOAJQSX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421202   

TargetGlucocorticoid receptor(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421202(CHEMBL2087291)
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after overnight incubation by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421202(CHEMBL2087291)
Affinity DataIC50: 391nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in GRAF cells assessed as inhibition of dexamethasone-induced alkaline phosphatase exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421202(CHEMBL2087291)
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at glucocorticoid receptor in rat hepatocytes assessed as inhibition of dexamethasone-induced trypsine aminotransferase expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed