BDBM50420702 CHEMBL2087462

SMILES OC[C@@H](O)CONC(=O)c1ccc2cnsc2c1Nc1ccc(I)cc1F

InChI Key InChIKey=FOOQXAKAICKOPK-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420702   

LigandPNGBDBM50420702(CHEMBL2087462)
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420702(CHEMBL2087462)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation in human HCT116 cells after 2 hrs by immunoblotting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420702(CHEMBL2087462)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation in human A375 cells after 2 hrs by immunoblotting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed