BDBM50420678 CHEMBL2087056

SMILES COc1ccc(NC(=O)c2cc(C)ccc2C(C)C)cc1

InChI Key InChIKey=MBOVOFKXQJOBFR-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420678   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420678(CHEMBL2087056)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420678(CHEMBL2087056)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 0.25 uM icilin-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420678(CHEMBL2087056)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of rat TRPM8 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420678(CHEMBL2087056)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of rat TRPA1 expressed in HEK293 cells assessed as reduction in 100 uM allyl isothiocyanate-stimulated increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50420678(CHEMBL2087056)
Affinity DataEC50:  1.24E+4nMAssay Description:Activation of rat TRPA1 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed