BDBM50420540 CHEMBL2086964

SMILES COc1cc(\C=N\NC(=O)c2cc3c(ccc4ccccc34)o2)cc(OC)c1O

InChI Key InChIKey=ICEFORRNJVZCHJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50420540   

TargetAndrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 2.63E+4nMAssay Description:Antagonist activity at wild type AR LBD assessed as inhibition of DHT-induced fluorescent labeled D11-FxxLF recruitment after 2 to 4 hrs by TR-FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of fluorescent labelled SRC1-4 from dexamethasone-GR complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of fluorescent labelled PGC-1alpha from estradiol-ERalpha complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of fluorescent labelled PGC-1alpha from estradiol-ERbeta complex after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 2.77E+4nMAssay Description:Antagonist activity at PR assessed as inhibition of progesterone-induced fluorescent labelled SRC1-4 recruitment after 2 to 4 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 2.63E+4nMAssay Description:Antagonist activity at wild-type human Androgen receptor measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50420540(CHEMBL2086964)
Affinity DataIC50: 3.32E+4nMAssay Description:Antagonist activity at human Androgen receptor T877A mutant measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed