BDBM50420475 CHEMBL2089396

SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC(CNC(=O)OCc2ccccc2)CC1

InChI Key InChIKey=YRNGWIRXJKRYIH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50420475   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420475(CHEMBL2089396)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase E(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420475(CHEMBL2089396)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of thrombin activated human TG3 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCoagulation factor XIII A chain(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420475(CHEMBL2089396)
Affinity DataIC50: 440nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase K(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50420475(CHEMBL2089396)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant TG1 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed