BDBM50420314 CHEMBL2089107

SMILES Cc1nc(=O)c2sc(nc2n1Cc1cccc(Cl)c1C)N1CCOCC1

InChI Key InChIKey=VGTBFMMMRGCJCS-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420314   

LigandPNGBDBM50420314(CHEMBL2089107)
Affinity DataEC50:  19nMAssay Description:Inhibition of PI3K beta in human PTEN-deficient MDA-MB-468 cells assessed as inhibition of Akt Ser473 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420314(CHEMBL2089107)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3K gamma by continuous TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420314(CHEMBL2089107)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3K delta by continuous TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420314(CHEMBL2089107)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3K beta by continuous TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420314(CHEMBL2089107)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3K alpha by continuous TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed