BDBM50420297 CHEMBL2089032

SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(NC[C@@H](O)CO)nc12

InChI Key InChIKey=BIUDJFOTQAVFMN-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50420297   

LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 180nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed