BDBM50420257 CHEMBL1236749::US20230322715, Compound ALK-07

SMILES CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(O)=O

InChI Key InChIKey=NGHVIOIJCVXTGV-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420257   

TargetRNA demethylase ALKBH5(Human)
University of California

US Patent
LigandPNGBDBM50420257(CHEMBL1236749 | US20230322715, Compound ALK-07)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of California

US Patent
LigandPNGBDBM50420257(CHEMBL1236749 | US20230322715, Compound ALK-07)
Affinity DataIC50: 4.00E+4nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
Go to US Patent

TargetPeptidase(Staphylococcus aureus)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50420257(CHEMBL1236749 | US20230322715, Compound ALK-07)
Affinity DataIC50: 7.00E+6nMAssay Description:Inhibition of Staphylococcus aureus PBP2aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 15 member 1(Human)
Biozentrum of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50420257(CHEMBL1236749 | US20230322715, Compound ALK-07)
Affinity DataKi: >3.00E+7nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 15 member 2(Rat)
Biozentrum of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50420257(CHEMBL1236749 | US20230322715, Compound ALK-07)
Affinity DataKi:  1.90E+7nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed